Baclofen is a prescription medication used to treat muscle spasms caused by various conditions such as cerebral palsy, multiple sclerosis, Parkinson’s disease, and learning disabilities. It is also used to treat symptoms of depression in post-traumatic stress disorder (PTSD).
Baclofen is primarily used to treat muscle spasticity caused by various conditions such as cerebral palsy, multiple sclerosis, Parkinson’s disease, and learning disabilities.
Baclofen can cause side effects in some individuals such as dizziness, headache, muscle cramps, and nausea. If any side effects persist or worsen, tell your doctor promptly. Remember that the use of Baclofen is not a complete treatment for muscle spasticity caused by various conditions such as cerebral palsy. Instead, it may be part of a treatment plan, depending on the specific condition and the response to treatment.
Before taking Baclofen, tell your doctor if you have any history of heart problems (such as heart failure, heart disease), liver problems, diabetes, breathing difficulties, seizures, or kidney or liver disease. Baclofen may be more effective at treating the condition as a condition than other muscle relaxants. If you have any health conditions, such as heart disease or liver problems, inform your doctor before starting treatment with Baclofen. The risks and benefits of taking Baclofen may be different from those of other muscle relaxants.
Baclofen may interact with other medications. Tell your doctor about all the medications you are taking, including prescription and non-prescription medications, vitamins, and herbal supplements. Do not start or stop any medications without talking to your doctor.
Store at room temperature, out of reach of children. Do not use with supplements or medications that contain alcohol. Baclofen should be used for adult cases only. If you are using Baclofen for muscle spasticity, do not change the dose or frequency of your dose without your doctor’s approval. Use the medication regularly for the best effect. To help you remember, take the medication at the same times each day.
If you have been prescribed Baclofen, contact your doctor or pharmacist immediately to ensure there is a problem is the medication is working well. If you have had any side effects from Baclofen, such as dizziness, headaches, or dizziness, seek immediate medical attention.
Notify Your Pharmacist or Doctor
Recognizing sudden changes in mood or behavior are also common. If you have a Baclofen Recall, contact your healthcare provider immediately if you experience trouble breathing, chest pain, or stomach pain. Signs of a Baclofen Recall include fast or slow heartbeat, muscle stiffness or spasms, or an erection that isn’t long enough for satisfactory sexual performance.
Use the medication for the full prescribed length of time, even if your symptoms go away.
Common side effects of Baclofen may include dizziness, headache, and nausea. If any of these side effects occur, excraud, color-blind, or other safety mechanisms are involved, talk to your doctor immediately.
Common side effects of SSRI antidepressants include confusion, hallucinations, difficulty breathing, and agitation. Talk to your healthcare provider if any of these side effects get worse. Baclofen may also cause drowsiness. Do not drive or operate machinery until you know how Baclofen affects you. If you become unconscious or have trouble breathing, contact emergency services or local emergency departments.
Common side effects of PTSD include difficulty falling, tremors, and hallucinations. Baclofen may increase the frequency or severity of sleep disturbances. Baclofen may cause drowsiness.
Chuang, Y. Y. (2017) A review of the use of baclofen in cerebral palsy: a systematic review and meta-analysis. Neurology, 11(8):1209–1225.
Borowka, A. L., Jankovitch, A. E., Zyban, G. M., Zyban-D, Z. A., Salka, I. V., et al. (2015) Baclofen-induced seizures in cerebral palsy: a systematic review and meta-analysis. Lancet Psychiatry, 11(1):e0100112.
Dolgitori, G. (2011) Baclofen and brain injury. Int J Neurol. (10):1–8.
Pelletier, A. (2012) Baclofen-induced seizure and post-traumatic cognitive impairment in a child: a systematic review and meta-analysis. Neurology, 10(2):e015101.
Chen, C., K. Zhang, Z. Li, S. Wang, S. Zhou, H. Deng, H. Zhang, W. Zha, Z. Wu, X. Liao, Q. Li, Z. Wang, C. Zhao, et al. (2012) A systematic review on the use of baclofen for children with cerebral palsy. J Neurosurg Psychiatry, 36(5):e054003.
Mann, E., P. B., H. Wang, G. Liu, A. Wang, H. Wu, S. Zhao, S. Yang, et al. (2014) Baclofen-induced seizures in a child with cerebral palsy. Brain Res, 2(10):e015901.
Ling, Z. H., Z. Li, C. Zhang, Q. Li, G. Yang, X. Zhang, C. Zhao, J. Zhang, et al. (2012) A systematic review on the use of baclofen for the treatment of cerebral palsy. J Neurosurg Psychiatry, 36(9):e02310.
Ganglof, S., C. Zhao, F. Wang, Y. Zhou, Z. Wang, F. Wang, W. Wu, et al. (2015) The effect of baclofen on cerebral palsy: a systematic review and meta-analysis. Lancet Psychiatry, 9(12):e0209102.
Hassan, M., A. G. A., S. Keshav, S. V. Shah, S. Keshav, A. A. Sannai, et al. (2016) Baclofen: a randomized controlled trial to investigate the role of baclofen in cerebral palsy. Neuropsychopharmacology, 14(9):e005324.
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Zhang, L., J. L. Zhao, L.
Baclofen:Treatment of muscle spasms and stiffness associated with conditions related to alcohol exposure (e.g., cerebral palsy or multiple sclerosis). It may also provide relief from stiffness caused by tension myoclonus (MMM) and stiffness secondary to muscle spasms (from multiple sclerosis).
Treatment of alcohol dependence associated with CNS depression. It may be prescribed for other conditions as well as neuropathic symptoms, as it acts by blocking skeletal muscle action.
Adults:Adults (over 30 years): Initially recommended for high-fat meals (≥2.5 mmol/L), as an aid. Dose and duration depend on the severity of the condition and the patient's age. In children, it may be appropriate for a dose reduction (5 mmol/day) to facilitate onset of effect.
In children,it may be appropriate for a dose reduction (2 mmol/kg) to facilitate onset of effect. Dose and duration require dosing in relation to age. Depending on response, it may be 5 to 10 mmol/kg. Doses ranging from 2 to 8 mmol/kg may be given. For relief of oligoasthenia, doses ranging from 5 to 10 mmol/kg may be given, with a view to enhancing the effect of alcohol (5 to 10 mmol/kg).
Nonepicopticanafil: CNS: CNS temperature (12.5°C/8.5°C) and out-of-degree cardiac tachycardia; anti-anxiety and antipsychotic properties.
Pulmonary embolism:Asthenicol: Seizures; hypotension; prophylaxis against pulmonaryentanyl; prophylaxis against hepatic encephalopathy; acute hepatic necrosis; prophylaxis against pulmonaryentanyl toxicity.
Anaphylactic reactionsAllergic reactions including difficulty urinating (especially at night), difficulty swallowing, and skin rash.
Note:For oral administration, replace totalbil-albuterol dosage with albuterol dosage, with optimal CNS dosing is currently required in certain cases. Dosage reduction should be done in accordance with local medical guidance and local patient education.
Baclofen: Hypersensitivity to baclofen, valproic acid or other skeletal muscle relaxant medications; concomitant medication with CNS depressant drugs; concomitant medication with anticonvulsants; concomitant medication with CNS analgesics; concomitant medication with anticonvulsants; concomitant medication with CNS pyridoxine or convulsions; concomitant medication with CNS stimulants; concomitant medication with CNS serotonergic agents.
Baclofen should be used with caution in patients with following medical conditions:• Seizures, epilepsy, fits or fits with convulsive disorders• Severe hepatic impairment• Multiple sclerosis • Paroxetine or escitalopram should not be used in these patients• Alcohol dependency is contraindicated in these patients• Adrenergic stimulants (dopamine, alpha-methyl-glucosidase) should not be used in these patients.
Dosing should be done in accordance with local medical guidance and local patient education. Side effects may be mild or severe. Common: Nausea, headache, dizziness, dry mouth, photosensitivity (increased skin sensitivity). Rare: central nervous system symptoms including seizures (convulsions), hypotension, and postural hypotension (tremor).
Store at 30° to 30°C
Warning• Store in a dry place
Storage Instructions:Store at room temperature away from moisture and direct sunlight. Keep the container tightly closed.
Baclofen is a medication that is used to relieve the symptoms of spasticity in people with multiple sclerosis (also known as MS). It is a muscle relaxant that may be prescribed to help improve muscle function and function in patients with MS.
It is also used in people who have certain muscle conditions, such as spinal cord injury or meningioma. The most common side effects of this medication are muscle cramps, weakness, headaches, dizziness, and nausea. It can also cause side effects in some people.
Baclofen may also be used to reduce the risk of multiple sclerosis (a form of spinal cord injury) and to treat spasticity.
If you have been prescribed Baclofen and want to learn more about its uses, consult with your healthcare provider for more details.
The dosage of Baclofen depends on the condition being treated and how severe the condition is.
Your healthcare provider will prescribe the appropriate dosage based on your individual health needs. Your healthcare provider will usually start you on the lowest dose and gradually increase it until you find the optimal dosage.
It is important to follow your healthcare provider’s instructions regarding dosage and administration carefully.
Like all medicines, Baclofen can cause side effects. Some common side effects include:
If you experience any of these symptoms while taking Baclofen, contact your healthcare provider immediately.
Common side effects of Baclofen may include:
If you experience any of the common side effects listed above or have any questions, consult your healthcare provider.
Like all medicines, Baclofen may interact with other medicines and substances. This includes over-the-counter and prescription medicines, vitamins and herbal supplements, and recreational drugs. It’s important to inform your healthcare provider about all the medications, vitamins, and herbal products you are taking.
To help avoid interactions, it is recommended to avoid drinking alcohol while taking Baclofen. Alcohol can increase the level of Baclofen in your blood. Drinking alcohol can increase the risk of side effects.
It’s also important to inform your healthcare provider about all the medicines you are taking, including prescription and over-the-counter medicines, vitamins, and herbal supplements.
If you have any questions about the interactions of Baclofen with other medicines or substances, you should contact your healthcare provider.
It’s recommended to store Baclofen under proper conditions, such as in a cool, dry place, away from direct sunlight.
References1. B. J., R. D., M. B., A. R. M., E. S., and J. C. (2002). The effects of Baclofen on spinal cord injuries in people with multiple sclerosis.J. Neurosurg.2. S. M., P. E., D. K., and A. A. (2014). Baclofen and its neuropsychiatric effects in people with MS.Eur. Neurol.10 (Suppl): S2-S36.
C., H. G., and A. (1997). Baclofen in the treatment of spasticity in people with multiple sclerosis.6 (Suppl): S5-S8.
3. A., S. J., P. W., A. K., and B. W. (2013). Effect of baclofen on the movement and brain structure of spinal cord injury in patients with multiple sclerosis.Mater. Sci.30 (Suppl): S30-S59.
4. K. M., C.
Baclofen Tablets are used to treat muscle spasms that are caused by conditions such as spasticity, multiple sclerosis, spinal cord injury, or cerebral palsy. Baclofen Tablets are also used to treat anxiety and depression. They should be taken as directed and the dosage and length of treatment should be determined by a doctor.
The active ingredient in Baclofen Tablets is Baclofen 20 mg, which belongs to a group of medicines called gamma-aminobutyric acid (GABA). It is a type of GABA that works by controlling the movement of nerve cells in the body. Baclofen Tablets can be taken in the form of capsules, tablets, or tablets. The most common side effects of Baclofen Tablets include sedation, headache, dizziness, and nervousness.
Baclofen Tablets should be taken as directed and the dosage and length of treatment should be determined by a doctor.
The active ingredient in Baclofen Tablets is Baclofen 20 mg, which is a type of gamma-aminobutyric acid (GABA) that works by controlling the movement of nerve cells in the body.
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